TMPRSS11D anticorps (N-Term)

N° du produit ABIN2782621

Cité dans 1 publication. Cet anticorps anti-TMPRSS11D Polyclonal Lapin (ABIN2782621) détecte spécifiquement TMPRSS11D dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Cobaye, Cheval et Lapin.

Aperçu rapide pour TMPRSS11D anticorps (N-Term) (ABIN2782621)

Antigène: TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))

Reactivité: Humain, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMPRSS11D est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TMPRSS11D anticorps

Épitope: N-Term

Fonction: TMPRSS11D Antibody - N-terminal region

Séquence: RSSFQLLNVE YNSQLNSPAT QEYRTLSGRI ESLITKTFKE SNLRNQFIRA

Homologie: Guinea Pig: 79%, Horse: 79%, Human: 100%, Rabbit: 79%

Attributs du produit: This is a rabbit polyclonal antibody against TMPRSS11D. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS11D

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114409

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TMPRSS11D (ABIN2782621)

Matsushima, Takahashi, Nakaya, Maezawa, Miki, Nakamura, Ohgushi, Yasuoka: "Human airway trypsin-like protease stimulates human bronchial fibroblast proliferation in a protease-activated receptor-2-dependent pathway." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 290, Issue 2, pp. L385-95, (2006) (PubMed).

Détails sur TMPRSS11D

Antigène: TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))

Autre désignation: TMPRSS11D

Sujet:

Background Information: TMPRSS11D is a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38 % identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38 % identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.

Gene Name: Transmembrane protease, serine 11D

Alternative Symbols: ASP, HAT

Protein Name: Transmembrane protease serine 11D

Poids moléculaire: 46kDa

ID gène: 9407

NCBI Accession: NP_004253

UniProt: O60235

Pathways: Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process