TMPRSS11D anticorps (N-Term)

N° du produit ABIN2782621

Détail du produit anti-TMPRSS11D anticorps

Antigène: TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))

Épitope: N-Term

Reactivité: Humain, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMPRSS11D est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: RSSFQLLNVE YNSQLNSPAT QEYRTLSGRI ESLITKTFKE SNLRNQFIRA

Homologie: Guinea Pig: 79%, Horse: 79%, Human: 100%, Rabbit: 79%

Attributs du produit: This is a rabbit polyclonal antibody against TMPRSS11D. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS11D

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 418 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TMPRSS11D (ABIN2782621)

Matsushima, Takahashi, Nakaya, Maezawa, Miki, Nakamura, Ohgushi, Yasuoka: "Human airway trypsin-like protease stimulates human bronchial fibroblast proliferation in a protease-activated receptor-2-dependent pathway." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 290, Issue 2, pp. L385-95, (2006) (PubMed).

Détails sur TMPRSS11D

Antigène: TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))

Autre désignation: TMPRSS11D (TMPRSS11D Produits)

Synonymes: anticorps HAT, anticorps AST, anticorps AsP, anticorps BC020151, anticorps Asp, anticorps Tmprss11d, anticorps transmembrane protease, serine 11D, anticorps transmembrane protease, serine 11d, anticorps transmembrane protease serine 11D, anticorps TMPRSS11D, anticorps Tmprss11d, anticorps LOC100720850

Sujet: TMPRSS11D is a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38 % identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38 % identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.
Alias Symbols: HAT, MGC150587, MGC150588
Protein Size: 418

Poids moléculaire: 46 kDa

ID gène: 9407

NCBI Accession: NM_004262, NP_004253

UniProt: O60235

Pathways: Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process