ALDH6A1 anticorps (Middle Region)

N° du produit ABIN2782682

Détail du produit anti-ALDH6A1 anticorps

Antigène: ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALDH6A1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GQVGVNVPIP VPLPMFSFTG SRSSFRGDTN FYGKQGIQFY TQLKTITSQW

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ALDH6A1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ALDH6A1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 535 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ALDH6A1 (ABIN2782682)

Kuiper, Williams, Distl, Drögemüller: "Assignment of the PAX6 gene to bovine chromosome 15q25-->q27 by fluorescence in situ hybridization and confirmation by radiation hybrid mapping." dans: Cytogenetic and genome research, Vol. 109, Issue 4, pp. 533, (2005) (PubMed).

Détails sur ALDH6A1

Antigène: ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

Autre désignation: ALDH6A1 (ALDH6A1 Produits)

Synonymes: anticorps MMSADHA, anticorps MMSDH, anticorps Mmsdh, anticorps cb850, anticorps wu:fb03a04, anticorps zgc:92082, anticorps 1110038I05Rik, anticorps AI314632, anticorps aldehyde dehydrogenase 6 family member A1, anticorps aldehyde dehydrogenase 6 family, member A1, anticorps aldehyde dehydrogenase 6 family member A1 L homeolog, anticorps methylmalonic acid semialdehyde dehydrogenase, anticorps methylmalonate-semialdehyde dehydrogenase (CoA acylating), anticorps aldehyde dehydrogenase family 6, subfamily A1, anticorps ALDH6A1, anticorps Aldh6a1, anticorps aldh6a1.L, anticorps CCNA_02357, anticorps aldh6a1, anticorps VAA_RS07845

Sujet: ALDH6A1 plays a role in valine and pyrimidine metabolism. ALDH6A1 binds fatty acyl-CoA. This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
Alias Symbols: MGC40271, MMSADHA, MMSDH
Protein Interaction Partner: UBC, LMO2,
Protein Size: 535

Poids moléculaire: 58 kDa

ID gène: 4329

NCBI Accession: NM_005589, NP_005580

UniProt: Q02252

Pathways: Brown Fat Cell Differentiation