ALDH6A1 anticorps (Middle Region)

N° du produit ABIN2782682

Il existe 1 publication pour ce produit. L’anticorps anti-ALDH6A1 Polyclonal Lapin est utilisé pour la détection de ALDH6A1 dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Porc, Lapin, Cobaye et Poisson zèbre (Danio rerio). Il a été validé pour WB et IHC.

Aperçu rapide pour ALDH6A1 anticorps (Middle Region) (ABIN2782682)

Antigène: ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Porc, Lapin, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALDH6A1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ALDH6A1 anticorps

Épitope: Middle Region

Fonction: ALDH6A1 Antibody - middle region

Séquence: GQVGVNVPIP VPLPMFSFTG SRSSFRGDTN FYGKQGIQFY TQLKTITSQW

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ALDH6A1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ALDH6A1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46619-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ALDH6A1 (ABIN2782682)

Kuiper, Williams, Distl, Drögemüller: "Assignment of the PAX6 gene to bovine chromosome 15q25-->q27 by fluorescence in situ hybridization and confirmation by radiation hybrid mapping." dans: Cytogenetic and genome research, Vol. 109, Issue 4, pp. 533, (2005) (PubMed).

Détails sur ALDH6A1

Antigène: ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

Autre désignation: ALDH6A1

Sujet:

Background Information: ALDH6A1 plays a role in valine and pyrimidine metabolism. ALDH6A1 binds fatty acyl-CoA. This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.

Gene Name: Aldehyde dehydrogenase 6 family, member A1

Alternative Symbols: MMSDH, MMSADHA

Protein Name: Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial

Poids moléculaire: 58kDa

ID gène: 4329

NCBI Accession: NP_005580

UniProt: Q02252

Pathways: Brown Fat Cell Differentiation