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BACE2 anticorps (Middle Region)

BACE2 Reactivité: Humain, Rat, Souris, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2782767
  • Antigène Voir toutes BACE2 Anticorps
    BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
    Épitope
    • 15
    • 9
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 50
    • 33
    • 12
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin, Poisson zèbre (Danio rerio)
    Hôte
    • 68
    • 3
    • 1
    Lapin
    Clonalité
    • 70
    • 2
    Polyclonal
    Conjugué
    • 32
    • 11
    • 8
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BACE2 est non-conjugé
    Application
    • 53
    • 35
    • 25
    • 13
    • 13
    • 12
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB)
    Séquence
    SLNLDCREYN ADKAIVDSGT TLLRLPQKVF DAVVEAVARA SLIPEFSDGF
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Zebrafish: 92%
    Attributs du produit
    This is a rabbit polyclonal antibody against BACE2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human BACE2
    Top Product
    Discover our top product BACE2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 396 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
    Autre désignation
    BACE2 (BACE2 Produits)
    Synonymes
    anticorps AEPLC, anticorps ALP56, anticorps ASP1, anticorps ASP21, anticorps BAE2, anticorps CEAP1, anticorps DRAP, anticorps 1110059C24Rik, anticorps AI850424, anticorps ARP1, anticorps CDA13, anticorps beta-site APP-cleaving enzyme 2, anticorps BACE2, anticorps Bace2
    Sujet
    Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.
    Alias Symbols: AEPLC, ALP56, ASP1, ASP21, BAE2, CDA13, CEAP1, DRAP
    Protein Interaction Partner: UBC, BACE2, APP, GGA1, GGA2,
    Protein Size: 396
    Poids moléculaire
    37 kDa
    ID gène
    25825
    NCBI Accession
    NM_138992, NP_620477
    UniProt
    Q9Y5Z0
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