BACE2 anticorps (N-Term)

N° du produit ABIN2782768

Cet anticorps anti-BACE2 Polyclonal Lapin (ABIN2782768) détecte spécifiquement BACE2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Cobaye et Boeuf (Vache).

Aperçu rapide pour BACE2 anticorps (N-Term) (ABIN2782768)

Antigène: BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

Reactivité: Humain, Rat, Souris, Cobaye, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BACE2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BACE2 anticorps

Épitope: N-Term

Fonction: BACE2 Antibody - N-terminal region

Séquence: PAGAANFLAM VDNLQGDSGR GYYLEMLIGT PPQKLQILVD TGSSNFAVAG

Homologie: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against BACE2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human BACE2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46853-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur BACE2

Antigène: BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

Autre désignation: BACE2

Sujet:

Background Information: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.

Gene Name: Beta-site APP-cleaving enzyme 2

Alternative Symbols: ASP1, BAE2, DRAP, AEPLC, ALP56, ASP21, CDA13, CEAP1

Protein Name: Beta-secretase 2

Poids moléculaire: 37kDa

ID gène: 25825

NCBI Accession: NP_620477

UniProt: Q9Y5Z0