PCDH12 anticorps (Middle Region)

N° du produit ABIN2782896

Cet anticorps Lapin Polyclonal détecte spécifiquement PCDH12 dans WB. Il présente une réactivité avec des échantillons de Rat, Humain, Boeuf (Vache), Cobaye, Cheval, Chien et Porc.

Aperçu rapide pour PCDH12 anticorps (Middle Region) (ABIN2782896)

Antigène: PCDH12 (Protocadherin 12 (PCDH12))

Reactivité: Rat, Humain, Boeuf (Vache), Cobaye, Cheval, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDH12 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PCDH12 anticorps

Épitope: Middle Region

Fonction: PCDH12 Antibody - middle region

Séquence: SSRPFLLTTI VARDADSGAN GEPLYSIRSG NEAHLFILNP HTGQLFVNVT

Homologie: Cow: 85%, Dog: 92%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Pig: 92%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PCDH12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PCDH12

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47275-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PCDH12

Antigène: PCDH12 (Protocadherin 12 (PCDH12))

Autre désignation: PCDH12

Sujet:

Background Information: PCDH12 belongs to the protocadherin protein family, a subfamily of the cadherin superfamily. It consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.

Gene Name: Protocadherin 12

Alternative Symbols: DMJDS1, VECAD2, VE-cadherin-2

Protein Name: Protocadherin-12

Poids moléculaire: 126kDa

ID gène: 51294

NCBI Accession: NP_057664

UniProt: Q9NPG4

Pathways: Cellular Glucan Metabolic Process