PCDH12 anticorps (N-Term)

N° du produit ABIN500453

Détail du produit anti-PCDH12 anticorps

Antigène: PCDH12 (Protocadherin 12 (PCDH12))

Épitope: N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDH12 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects PCDH12. It is predicted to not cross-react with PCDH18.

Purification: Peptide affinity chromatography

Immunogène: PCDH12 antibody was raised against a 17 amino acid peptide near the amino terminus of human PCDH12.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PCDH12

Antigène: PCDH12 (Protocadherin 12 (PCDH12))

Autre désignation: Protocadherin-12 / PCDH12 (PCDH12 Produits)

Synonymes: anticorps PCDH12, anticorps VE-cadherin-2, anticorps VECAD2, anticorps Pcdh14, anticorps VE-cad-2, anticorps protocadherin 12, anticorps PCDH12, anticorps Pcdh12

Sujet: Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA, further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2,289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling.Synonyms: VE-cad-2, VE-cadherin-2, Vascular cadherin-2, Vascular endothelial cadherin-2

ID gène: 51294

NCBI Accession: NP_057664

UniProt: Q9NPG4

Pathways: Cellular Glucan Metabolic Process