PCDH12 anticorps (N-Term)

N° du produit ABIN6991078

Cet anticorps Lapin Polyclonal détecte spécifiquement PCDH12 dans WB, ELISA et IHC (p). Il présente une réactivité avec des échantillons de Rat, Humain et Souris.

Aperçu rapide pour PCDH12 anticorps (N-Term) (ABIN6991078)

Antigène: PCDH12 (Protocadherin 12 (PCDH12))

Reactivité: Rat, Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDH12 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PCDH12 anticorps

Épitope: AA 30-80, N-Term

Specificité: This antibody is predicted to not cross-react with PCDH18.

Purification: PCDH12 Antibody is affinity chromatography purified via peptide column.

Immunogène: PCDH12 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human PCDH12. The immunogen is located within amino acids 30 - 80 of PCDH12.

Isotype: IgG

Information d'application

Indications d'application: PCDH12 antibody can be used for detection of PCDH12 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PCDH12 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PCDH12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PCDH12

Antigène: PCDH12 (Protocadherin 12 (PCDH12))

Autre désignation: PCDH12

Sujet: PCDH12 Antibody: Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA, further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2, 289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling.

Poids moléculaire: Predicted: 128 kDa

Observed: 125 kDa

ID gène: 51294

NCBI Accession: NP_057664

UniProt: Q9NPG4

Pathways: Cellular Glucan Metabolic Process