Frataxin anticorps (Middle Region)

N° du produit ABIN785388

Cet anticorps anti-Frataxin est un anticorps Lapin Polyclonal détectant Frataxin dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien et Cobaye.

Aperçu rapide pour Frataxin anticorps (Middle Region) (ABIN785388)

Antigène: Frataxin (FXN)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Frataxin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Frataxin anticorps

Épitope: Middle Region

Séquence: TLDNPSSLDE TAYERLAEET LDSLAEFFED LADKPYTLED YDVSFGDGVL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against Fxn. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 207 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Frataxin

Antigène: Frataxin (FXN)

Autre désignation: Fxn

Sujet: Fxn promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. It may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. It may be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. It modulates the RNA-binding activity of ACO1.
Alias Symbols: FA, FARR, Frda, X25
Protein Size: 207

Poids moléculaire: 23 kDa

ID gène: 14297

NCBI Accession: NM_008044, NP_032070

UniProt: O35943

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size