Myosin 9 anticorps (Middle Region)

N° du produit ABIN2783216

Il existe 1 publication pour ce produit. L’anticorps anti-Myosin 9 Polyclonal Lapin est utilisé pour la détection de Myosin 9 dans des échantillons de Humain, Souris, Rat, Chien, Porc, Cobaye et Lapin. Il a été validé pour WB.

Aperçu rapide pour Myosin 9 anticorps (Middle Region) (ABIN2783216)

Antigène: Myosin 9 (MYH9)

Reactivité: Humain, Souris, Rat, Chien, Porc, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Myosin 9 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Myosin 9 anticorps

Épitope: Middle Region

Fonction: MYH9 Antibody - middle region

Séquence: DAMNREVSSL KNKLRRGDLP FVVPRRMARK GAGDGSDEEV DGKADGAEAK

Homologie: Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MYH9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MYH9

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48072-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Myosin 9 (ABIN2783216)

Sabbir, Dillon, Mowat: "Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activation." dans: Biology open, Vol. 5, Issue 4, pp. 452-60, (2016) (PubMed).

Détails sur Myosin 9

Antigène: Myosin 9 (MYH9)

Autre désignation: MYH9

Sujet:

Background Information: MYH9 is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.

Gene Name: Myosin, heavy chain 9, non-muscle

Alternative Symbols: MHA, FTNS, EPSTS, BDPLT6, DFNA17, MATINS, NMMHCA, NMHC-II-A, NMMHC-IIA

Protein Name: Myosin-9

Poids moléculaire: 226kDa

ID gène: 4627

NCBI Accession: NP_002464

UniProt: P35579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Integrin Complex