HLA-F anticorps (N-Term)
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- Antigène Voir toutes HLA-F (HLAF) Anticorps
- HLA-F (HLAF) (HLA Class I alpha F (HLAF))
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Épitope
- N-Term
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Reactivité
- Humain, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HLA-F est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- PWVEQEGPQY WEWTTGYAKA NAQTDRVALR NLLRRYNQSE AGSHTLQGMN
- Homologie
- Human: 100%, Pig: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against HLA-F. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human HLA-F
- Top Product
- Discover our top product HLAF Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 442 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- HLA-F (HLAF) (HLA Class I alpha F (HLAF))
- Autre désignation
- HLA-F (HLAF Produits)
- Synonymes
- anticorps HLAF, anticorps CDA12, anticorps HLA-5.4, anticorps HLA-CDA12, anticorps major histocompatibility complex, class I, F, anticorps HLA-F
- Sujet
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HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation.
Alias Symbols: CDA12, HLA-5.4, HLA-CDA12, HLAF
Protein Interaction Partner: UBC, LILRB2, LILRB1, TAP1, HLA-F, B2M,
Protein Size: 442 - Poids moléculaire
- 48 kDa
- ID gène
- 3134
- NCBI Accession
- NM_001098479, NP_001091949
- UniProt
- Q5JQI8
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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