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LRRC8A anticorps (N-Term)

Cet anticorps anti-LRRC8A est un anticorps Lapin Polyclonal détectant LRRC8A dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).
N° du produit ABIN2783752

Aperçu rapide pour LRRC8A anticorps (N-Term) (ABIN2783752)

Antigène

Voir toutes LRRC8A Anticorps
LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

Reactivité

  • 19
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte

  • 15
  • 4
Lapin

Clonalité

  • 15
  • 4
Polyclonal

Conjugué

  • 11
  • 2
  • 2
  • 2
  • 1
  • 1
Cet anticorp LRRC8A est non-conjugé

Application

  • 19
  • 10
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Séquence

    IPVTELRYFA DTQPAYRILK PWWDVFTDYI SIVMLMIAVF GGTLQVTQDK

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    Attributs du produit

    This is a rabbit polyclonal antibody against LRRC8A. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human LRRC8A
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 810 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

    Autre désignation

    LRRC8A

    Sujet

    LRRC8A is a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. LRRC8A is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
    Alias Symbols: FLJ10337, KIAA1437, LRRC8, AGM5
    Protein Interaction Partner: SDHA, ELAVL1, UBC,
    Protein Size: 810

    Poids moléculaire

    94 kDa

    ID gène

    56262

    NCBI Accession

    NM_019594, NP_062540

    UniProt

    Q8IWT6
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