LRRC8A anticorps (N-Term)

N° du produit ABIN6992155

Détail du produit anti-LRRC8A anticorps

Antigène: LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

Épitope: AA 60-110, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC8A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: LRRC8A antibody is human, mouse and rat reactive.

Purification: LRRC8A antibody is affinity chromatography purified via peptide column.

Immunogène: LRRC8A antibody was raised against a 15 amino acid peptide near the amino terminus of human LRRC8A. The immunogen is located within amino acids 60 - 110 of LRRC8A.

Isotype: IgG

Information d'application

Indications d'application: LRRC8A antibody can be used for detection of LRRC8A by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: LRRC8A antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: LRRC8A antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur LRRC8A

Antigène: LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

Autre désignation: LRRC8A (LRRC8A Produits)

Synonymes: anticorps AGM5, anticorps LRRC8, anticorps Lrrc8, anticorps mKIAA1437, anticorps wu:fb18g12, anticorps wu:fi21b10, anticorps LLRC8A, anticorps leucine rich repeat containing 8 VRAC subunit A, anticorps leucine rich repeat containing 8A, anticorps leucine rich repeat containing 8 VRAC subunit Aa, anticorps leucine-rich repeat containing 8 family member A S homeolog, anticorps leucine rich repeat containing 8 family member A, anticorps LRRC8A, anticorps Lrrc8a, anticorps lrrc8aa, anticorps lrrc8a.S

Sujet: The leucine rich repeat containing 8 family member A protein (LRRC8A) belongs the LRRC8 family of proteins within the LRR superfamily of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions (1,2). LRRC8A is a four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation (1). LRRC8A has also been shown to be an essential component of the volume-regulated anion channel VRAC (3).

Poids moléculaire: Predicted: 89 kDa

Observed: 95 kDa

ID gène: 56262

NCBI Accession: NP_062540

UniProt: Q8IWT6