PCDHA6 anticorps (C-Term)

N° du produit ABIN2784011

Cet anticorps Lapin Polyclonal détecte spécifiquement PCDHA6 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Cobaye, Cheval, Boeuf (Vache) et Chien.

Aperçu rapide pour PCDHA6 anticorps (C-Term) (ABIN2784011)

Antigène: PCDHA6 (Protocadherin alpha 6 (PCDHA6))

Reactivité: Humain, Rat, Souris, Cobaye, Cheval, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHA6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PCDHA6 anticorps

Épitope: C-Term

Fonction: PCDHA6 Antibody - C-terminal region

Séquence: LVKDHGEPAL TATATVLVSL VESGQAPKAS SRASVGAAGP EAALVDVNVY

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PCDHA6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human PCDHA6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50008-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PCDHA6

Antigène: PCDHA6 (Protocadherin alpha 6 (PCDHA6))

Autre désignation: PCDHA6

Sujet:

Background Information: PCDHA6 contains 6 cadherin domains. It is a potential calcium-dependent cell-adhesion protein. PCDHA6 may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Gene Name: Protocadherin alpha 6

Alternative Symbols: CNR2, CNRN2, CNRS2, CRNR2, PCDH-ALPHA6

Protein Name: Protocadherin alpha-6

Poids moléculaire: 84kDa

ID gène: 56142

NCBI Accession: NP_114036

UniProt: Q9UN73