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PCDHA6 anticorps (C-Term)

PCDHA6 Reactivité: Humain, Rat, Souris, Cobaye, Cheval, Boeuf (Vache), Chien WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2784011
  • Antigène Voir toutes PCDHA6 Anticorps
    PCDHA6 (Protocadherin alpha 6 (PCDHA6))
    Épitope
    • 15
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 37
    • 20
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Cobaye, Cheval, Boeuf (Vache), Chien
    Hôte
    • 46
    • 6
    Lapin
    Clonalité
    • 48
    • 4
    Polyclonal
    Conjugué
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PCDHA6 est non-conjugé
    Application
    • 28
    • 22
    • 14
    • 13
    • 13
    • 11
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Séquence
    LVKDHGEPAL TATATVLVSL VESGQAPKAS SRASVGAAGP EAALVDVNVY
    Homologie
    Cow: 86%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against PCDHA6. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human PCDHA6
    Top Product
    Discover our top product PCDHA6 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 803 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    PCDHA6 (Protocadherin alpha 6 (PCDHA6))
    Autre désignation
    PCDHA6 (PCDHA6 Produits)
    Synonymes
    anticorps CNR2, anticorps CNRN2, anticorps CNRS2, anticorps CRNR2, anticorps PCDH-ALPHA6, anticorps CNR, anticorps Cnr2, anticorps Crnr2, anticorps rCNRv06, anticorps PCDHA3, anticorps PCDHA6, anticorps PCDHA7, anticorps PCDHA9, anticorps protocadherin alpha 6, anticorps PCDHA6, anticorps Pcdha6
    Sujet
    PCDHA6 contains 6 cadherin domains. It is a potential calcium-dependent cell-adhesion protein. PCDHA6 may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
    Alias Symbols: CNR2, CNRN2, CNRS2, CRNR2, PCDH-ALPHA6
    Protein Interaction Partner: CUL3, UBC, RELN,
    Protein Size: 803
    Poids moléculaire
    84 kDa
    ID gène
    56142
    NCBI Accession
    NM_031848, NP_114036
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