ORAI1 anticorps (N-Term)

N° du produit ABIN2784057

Détail du produit anti-ORAI1 anticorps

Antigène: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Épitope: N-Term

Reactivité: Humain, Souris, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ORAI1 est non-conjugé

Application: Western Blotting (WB)

Séquence: HPEPAPPPSR SSPELPPSGG STTSGSRRSR RRSGDGEPPG APPPPPSAVT

Homologie: Horse: 83%, Human: 100%, Mouse: 79%

Attributs du produit: This is a rabbit polyclonal antibody against ORAI1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ORAI1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 301 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ORAI1

Antigène: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Autre désignation: ORAI1 (ORAI1 Produits)

Synonymes: anticorps CRACM1, anticorps ORAT1, anticorps TMEM142A, anticorps RGD1311873, anticorps D730049H07Rik, anticorps Tmem142a, anticorps orai-1, anticorps im:7146264, anticorps orai1, anticorps tmem142a, anticorps zgc:109721, anticorps orai2, anticorps ORAI1, anticorps LOC100218031, anticorps ORAI calcium release-activated calcium modulator 1, anticorps ORAI calcium release-activated calcium modulator 1b, anticorps ORAI calcium release-activated calcium modulator 1 S homeolog, anticorps ORAI1, anticorps Orai1, anticorps orai1b, anticorps orai1.S, anticorps orai1

Sujet: ORAI1 belongs to the Orai family. ORAI1 (CRACM1) is a plasma membrane protein essential for store-operated calcium entry. Defects in ORAI1 are a cause of severe combined immunodeficiency with CRAC channel dysfunction (CRAC-SCID).CRACM1 is a plasma membrane protein essential for store-operated calcium entry (Vig et al., 2006 [PubMed 16645049]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-331 BC075831.1 1-331 332-844 BC013386.1 220-732 845-990 BC075831.1 845-990 991-1490 BG574128.1 52-551 1491-1496 AK027372.1 1235-1240
Alias Symbols: CRACM1, FLJ14466, TMEM142A, ORAT1
Protein Interaction Partner: UBQLN1, UBC, TRPC3, TRPC6,
Protein Size: 301

Poids moléculaire: 33 kDa

ID gène: 84876

NCBI Accession: NM_032790, NP_116179

UniProt: Q96D31

Pathways: TCR Signaling, BCR Signaling