ORAI1 anticorps (Middle Region)

N° du produit ABIN2784058

Cet anticorps anti-ORAI1 est un anticorps Lapin Polyclonal détectant ORAI1 dans WB. Adapté pour Humain, Rat, Cheval, Porc, Boeuf (Vache), Chien, Lapin et Saccharomyces cerevisiae.

Aperçu rapide pour ORAI1 anticorps (Middle Region) (ABIN2784058)

Antigène: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Reactivité: Humain, Rat, Cheval, Porc, Boeuf (Vache), Chien, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ORAI1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ORAI1 anticorps

Épitope: Middle Region

Séquence: IGTLLFLAEV VLLCWVKFLP LKKQPGQPRP TSKPPASGAA ANVSTSGITP

Homologie: Cow: 93%, Dog: 100%, Horse: 93%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 86%, Yeast: 77%

Attributs du produit: This is a rabbit polyclonal antibody against ORAI1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ORAI1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 301 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ORAI1

Antigène: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Autre désignation: ORAI1

Sujet: ORAI1 belongs to the Orai family. ORAI1 (CRACM1) is a plasma membrane protein essential for store-operated calcium entry. Defects in ORAI1 are a cause of severe combined immunodeficiency with CRAC channel dysfunction (CRAC-SCID).CRACM1 is a plasma membrane protein essential for store-operated calcium entry (Vig et al., 2006 [PubMed 16645049]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-331 BC075831.1 1-331 332-844 BC013386.1 220-732 845-990 BC075831.1 845-990 991-1490 BG574128.1 52-551 1491-1496 AK027372.1 1235-1240
Alias Symbols: CRACM1, FLJ14466, TMEM142A, ORAT1
Protein Interaction Partner: UBQLN1, UBC, TRPC3, TRPC6,
Protein Size: 301

Poids moléculaire: 33 kDa

ID gène: 84876

NCBI Accession: NM_032790, NP_116179

UniProt: Q96D31

Pathways: TCR Signaling, BCR Signaling