GTF2H2 anticorps (N-Term)

N° du produit ABIN2784198

Cet anticorps anti-GTF2H2 Polyclonal Lapin (ABIN2784198) détecte spécifiquement GTF2H2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Cheval, Poisson zèbre (Danio rerio), Chien, Boeuf (Vache), Lapin et Cobaye.

Aperçu rapide pour GTF2H2 anticorps (N-Term) (ABIN2784198)

Antigène: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Reactivité: Humain, Souris, Rat, Cheval, Poisson zèbre (Danio rerio), Chien, Boeuf (Vache), Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GTF2H2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GTF2H2 anticorps

Épitope: N-Term

Séquence: SLKATIEDIL FKAKRKRVFE HHGQVRLGMM RHLYVVVDGS RTMEDQDLKP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against Gtf2h2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of mouse GTF2H2

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GTF2H2

Antigène: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Autre désignation: Gtf2h2

Sujet: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of this gene within the centromeric copy of the duplication has been described in the literature. It is reported to be different by either two or four base pairs, however, no sequence data is currently available for the centromeric copy of the gene.
Alias Symbols: p44, BTF2, TFIIH, BTF2P44, T-BTF2P44
Protein Size: 201

Poids moléculaire: 22 kDa

ID gène: 2966

NCBI Accession: NM_001515, NP_001506

UniProt: Q13888

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling