GTF2H2 anticorps (C-Term)
-
- Antigène Voir toutes GTF2H2 Anticorps
- GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))
-
Épitope
- C-Term
-
Reactivité
- Humain, Souris, Cheval, Poisson zèbre (Danio rerio), Chien
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp GTF2H2 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- CELPVECKIC GLTLVSAPHL ARSYHHLFPL DAFQEIPLEE YNGERFCYGC
- Réactivité croisée
- Boeuf (Vache), Chien, Poulet, Humain, Souris, Rat (Rattus)
- Homologie
- Dog: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Zebrafish: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against GTF2H2. It was validated on Western Blot.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2H2
- Top Product
- Discover our top product GTF2H2 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 395 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))
- Autre désignation
- GTF2H2 / BTF2P44 (GTF2H2 Produits)
- Synonymes
- anticorps 44kDa, anticorps BTF2 p44, anticorps BTF2-p44, anticorps Btf2p44, anticorps p44, anticorps BTF2, anticorps BTF2P44, anticorps T-BTF2P44, anticorps TFIIH, anticorps general transcription factor II H, polypeptide 2, anticorps general transcription factor IIH subunit 2, anticorps general transcription factor IIH, polypeptide 2, 44kDa, anticorps Gtf2h2, anticorps GTF2H2
- Sujet
-
GTF2 is encoded by a gene that is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of this gene within the centromeric copy of the duplication has been described in the literature. It is reported to be different by either two or four base pairs, however, no sequence data is currently available for the centromeric copy of the gene.
Alias Symbols: p44, BTF2, TFIIH, BTF2P44, T-BTF2P44
Protein Interaction Partner: UBC, CDK7, GTF2H5, GTF2H1, SRA1, GTF2H4, GTF2H3, UBD, COPS2, ERCC3, ERCC8, ERCC2, AR, MNAT1, CCNH,
Protein Size: 395 - Poids moléculaire
- 44 kDa
- ID gène
- 2966
- NCBI Accession
- NM_001515, NP_001506
- UniProt
- Q13888
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
-