FLASH anticorps (N-Term)

N° du produit ABIN2784233

Cet anticorps Lapin Polyclonal détecte spécifiquement FLASH dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Porc et Lapin et a été mentionné dans 1 publication.

Aperçu rapide pour FLASH anticorps (N-Term) (ABIN2784233)

Antigène: FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FLASH est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FLASH anticorps

Épitope: N-Term

Séquence: SLKKNISALI KTARVEINRK DEEISNLHQR LSEFPHFRNN HKTARTFDTV

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CASP8AP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CASP8AP2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1982 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-FLASH (ABIN2784233)

Lee, Pi, Lee: "Buffer optimization for high resolution of human lung cancer tissue proteins by two-dimensional gel electrophoresis." dans: Biotechnology letters, Vol. 31, Issue 1, pp. 31-7, (2008) (PubMed).

Détails sur FLASH

Antigène: FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))

Autre désignation: CASP8AP2

Sujet: CASP8AP2 is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis.This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CED-4, FLASH, FLJ11208, KIAA1315, RIP25
Protein Interaction Partner: ced-3, BCL2L1, PML, CTBP2, CREM, SUMO1, SUMO2, PIAS1, CASP10, TRIM21, UBC, CALM1, UBE2I, SREBF2, GLUL, SP100, CASP8AP2, FADD, TRAF2, CASP8, FAS,
Protein Size: 1982

Poids moléculaire: 223 kDa

ID gène: 9994

NCBI Accession: NM_012115, NP_036247

UniProt: Q9UKL3

Pathways: Chromatin Binding, Positive Regulation of Endopeptidase Activity