Frataxin anticorps (C-Term)

N° du produit ABIN2784465

L’anticorps anti-Frataxin Polyclonal Lapin est utilisé pour la détection de Frataxin dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye, Saccharomyces cerevisiae et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour Frataxin anticorps (C-Term) (ABIN2784465)

Antigène: Frataxin (FXN)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Frataxin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Frataxin anticorps

Épitope: C-Term

Fonction: Fxn Antibody - C-terminal region

Séquence: EFFEDLADKP YTLKDYDVSF GDGVLTIKLG GDLGTYVINK QTPNKQIWLS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against Fxn. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Rat

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51215-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Frataxin

Antigène: Frataxin (FXN)

Autre désignation: Fxn

Sujet:

Background Information: Fxn promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. It may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. It may be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Fxn modulates the RNA-binding activity of ACO1.

Gene Name: Frataxin

Alternative Symbols: RGD1565754

Protein Name: Frataxin, mitochondrial

Poids moléculaire: 23kDa

ID gène: 499335

NCBI Accession: XP_001078791

UniProt: D3ZYW7

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size