Aspartate beta Hydroxylase anticorps (N-Term)

N° du produit ABIN2784533

L’anticorps anti-Aspartate beta Hydroxylase Polyclonal Lapin est utilisé pour la détection de Aspartate beta Hydroxylase dans des échantillons de Humain, Souris, Rat, Chien, Cheval, Porc et Lapin. Il a été validé pour WB et IHC.

Aperçu rapide pour Aspartate beta Hydroxylase anticorps (N-Term) (ABIN2784533)

Antigène: Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aspartate beta Hydroxylase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Aspartate beta Hydroxylase anticorps

Épitope: N-Term

Fonction: ASPH Antibody - N-terminal region

Séquence: SEVLQGKLGI YDADGDGDFD VDDAKVLLEG PSGVAKRKTK AKVKELTKEE

Homologie: Dog: 93%, Horse: 83%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ASPH. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ASPH

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51357-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Aspartate beta Hydroxylase

Antigène: Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

Autre désignation: ASPH

Sujet:

Background Information: ASPH is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins.This gene is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins.

Gene Name: Aspartate beta-hydroxylase

Alternative Symbols: AAH, BAH, HAAH, JCTN, FDLAB, junctin, CASQ2BP1

Protein Name: Aspartyl/asparaginyl beta-hydroxylase

Poids moléculaire: 25kDa

ID gène: 444

NCBI Accession: NP_064549

UniProt: Q9NRI0

Pathways: Positive Regulation of Endopeptidase Activity