ALKBH2 anticorps (Middle Region)
Aperçu rapide pour ALKBH2 anticorps (Middle Region) (ABIN2784623)
Antigène
Voir toutes ALKBH2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- ALKBH2 Antibody - middle region
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Séquence
- VPRKQATYGD AGLTYTFSGL TLSPKPWIPV LERIRDHVSG VTGQTFNFVL
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against ALKBH2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human ALKBH2
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51778-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- ALKBH2 (AlkB, Alkylation Repair Homolog 2 (ALKBH2))
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Autre désignation
- ALKBH2
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Sujet
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Background Information: The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine.The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM].
Gene Name: AlkB, alkylation repair homolog 2 (E. coli)
Alternative Symbols: ABH2
Protein Name: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2
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Poids moléculaire
- 29kDa
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ID gène
- 121642
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NCBI Accession
- NP_001001655
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UniProt
- Q6NS38
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Pathways
- Réparation de l'ADN
Antigène
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