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CLK2 anticorps (N-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement CLK2 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).
N° du produit ABIN2784735

Aperçu rapide pour CLK2 anticorps (N-Term) (ABIN2784735)

Antigène

Voir toutes CLK2 Anticorps
CLK2 (CDC-Like Kinase 2 (CLK2))

Reactivité

  • 55
  • 37
  • 28
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte

  • 64
Lapin

Clonalité

  • 64
Polyclonal

Conjugué

  • 23
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CLK2 est non-conjugé

Application

  • 52
  • 28
  • 13
  • 13
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 15
    • 9
    • 7
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Séquence

    KFLHDNKLTH TDLKPENILF VNSDYELTYN LEKKRDERSV KSTAVRVVDF

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

    Attributs du produit

    This is a rabbit polyclonal antibody against CLK2. It was validated on Western Blot.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N-terminal region of human CLK2
  • Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeat freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    CLK2 (CDC-Like Kinase 2 (CLK2))

    Autre désignation

    CLK2

    Sujet

    This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29 kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.
    Protein Size: 271

    Poids moléculaire

    29 kDa

    ID gène

    1196

    NCBI Accession

    NM_001294339, NP_001281268

    UniProt

    B7Z8N6

    Pathways

    Regulation of Carbohydrate Metabolic Process
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