METAP2 anticorps (N-Term)

N° du produit ABIN2784850

Détail du produit anti-METAP2 anticorps

Antigène: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp METAP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: ATGKKKKKKK KKRGPKVQTD PPSVPICDLY PNGVFPKGQE CEYPPTQDGR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against METAP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human METAP2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 478 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur METAP2

Antigène: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Autre désignation: METAP2 (METAP2 Produits)

Synonymes: anticorps metap2, anticorps MGC53792, anticorps METAP2, anticorps GB13458, anticorps DDBDRAFT_0190923, anticorps DDBDRAFT_0304991, anticorps DDB_0190923, anticorps DDB_0304991, anticorps 4930584B20Rik, anticorps A930035J23Rik, anticorps AI047573, anticorps AL024412, anticorps AU014659, anticorps Amp2, anticorps Mnpep, anticorps p67, anticorps p67eIF2, anticorps MAP2, anticorps MNPEP, anticorps wu:fb98h06, anticorps zgc:66250, anticorps methionyl aminopeptidase 2 L homeolog, anticorps methionyl aminopeptidase 2, anticorps methionine aminopeptidase 2, anticorps methionine aminopeptidase, anticorps methionyl aminopeptidase 2 S homeolog, anticorps methionyl aminopeptidase 2b, anticorps metap2.L, anticorps METAP2, anticorps metap2, anticorps LOC551771, anticorps CAALFM_C604080WA, anticorps Metap2, anticorps metap2.S, anticorps metap2b

Sujet: METAP2 is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site.This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MAP2, MNPEP, p67, p67eIF2
Protein Interaction Partner: UBC, DAK, NPEPPS, GBP1, GAPDH, HMGA1, MTOR, EEF2K, APP, CALM1, S100A4, RAC1, MAPK3, EIF2S3, MAPK1, EIF2AK2, CDC42, E2F4,
Protein Size: 478

Poids moléculaire: 53 kDa

ID gène: 10988

NCBI Accession: NM_006838, NP_006829

UniProt: P50579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling