HSD17B3 anticorps (N-Term)

N° du produit ABIN2785439

Il existe 1 publication pour ce produit. L’anticorps anti-HSD17B3 Polyclonal Lapin est utilisé pour la détection de HSD17B3 dans des échantillons de Humain, Rat et Cheval. Il a été validé pour WB.

Aperçu rapide pour HSD17B3 anticorps (N-Term) (ABIN2785439)

Antigène: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Reactivité: Humain, Rat, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD17B3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HSD17B3 anticorps

Épitope: N-Term

Fonction: HSD17B3 Antibody - N-terminal region

Séquence: AVITGAGDGI GKAYSFELAK RGLNVVLISR TLEKLEAIAT EIERTTGRSV

Homologie: Horse: 79%, Human: 100%, Rat: 91%

Attributs du produit: This is a rabbit polyclonal antibody against HSD17B3. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53554-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HSD17B3 (ABIN2785439)

Bertin, Dury, Ouellet, Pelletier, Labrie: "Localization of the androgen-synthesizing enzymes, androgen receptor, and sex steroids in the vagina: possible implications for the treatment of postmenopausal sexual dysfunction." dans: The journal of sexual medicine, Vol. 11, Issue 8, pp. 1949-61, (2014) (PubMed).

Détails sur HSD17B3

Antigène: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Autre désignation: HSD17B3

Sujet:

Background Information: This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.

Gene Name: Hydroxysteroid (17-beta) dehydrogenase 3

Alternative Symbols: EDH17B3, SDR12C2

Protein Name: Testosterone 17-beta-dehydrogenase 3

Poids moléculaire: 34kDa

ID gène: 3293

NCBI Accession: NP_000188

UniProt: P37058

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis