GRK4 anticorps (Middle Region)

N° du produit ABIN2785447

Cet anticorps Lapin Polyclonal détecte spécifiquement GRK4 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio), Chien, Cobaye et Lapin.

Aperçu rapide pour GRK4 anticorps (Middle Region) (ABIN2785447)

Antigène: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio), Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRK4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GRK4 anticorps

Épitope: Middle Region

Séquence: QSRFVVSLAY AYETKDALCL VLTIMNGGDL KFHIYNLGNP GFDEQRAVFY

Homologie: Cow: 79%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against GRK4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GRK4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 532 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GRK4

Antigène: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Autre désignation: GRK4

Sujet: GRK4 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. GRK4 has been linked to both genetic and acquired hypertension.This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension.
Alias Symbols: GPRK2L, GPRK4, GRK4a, IT11
Protein Interaction Partner: HSP90AA1, UBC, NEDD4, IKBKG, FSHR, CALM1, BDKRB2,
Protein Size: 532

Poids moléculaire: 59 kDa

ID gène: 2868

NCBI Accession: NM_001004057, NP_001004057

UniProt: P32298

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling