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Aurora A anticorps (Middle Region)

Cet anticorps Lapin Polyclonal détecte spécifiquement Aurora A dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Mouton, Lapin, Chien, Cobaye, Cheval et Poisson zèbre (Danio rerio).
N° du produit ABIN2785452

Aperçu rapide pour Aurora A anticorps (Middle Region) (ABIN2785452)

Antigène

Voir toutes Aurora A (AURKA) Anticorps
Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reactivité

  • 113
  • 65
  • 37
  • 20
  • 18
  • 13
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
Humain, Souris, Rat, Boeuf (Vache), Mouton, Lapin, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte

  • 109
  • 18
  • 1
Lapin

Clonalité

  • 100
  • 27
Polyclonal

Conjugué

  • 79
  • 8
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Aurora A est non-conjugé

Application

  • 94
  • 47
  • 37
  • 26
  • 14
  • 13
  • 11
  • 10
  • 10
  • 3
  • 2
  • 1
Western Blotting (WB)
  • Épitope

    • 22
    • 11
    • 9
    • 8
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Séquence

    REKQSKFILA LKVLFKAQLE KAGVEHQLRR EVEIQSHLRH PNILRLYGYF

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 77%, Zebrafish: 79%

    Attributs du produit

    This is a rabbit polyclonal antibody against AURKA. It was validated on Western Blot.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the middle region of Human AURKA
  • Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeat freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    Aurora A (AURKA) (Aurora Kinase A (AURKA))

    Autre désignation

    AURKA

    Sujet

    AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. It is found at the centrosome in interphase cells and at the spindle poles in mitosis. This protein may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
    Alias Symbols: AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7
    Protein Interaction Partner: CHFR, GADD45A, RPLP2, RPLP0, RPL38, RPL30, RPL27, RPL22, RPL12, RPL11, PSMB7, PSMB5, PSMA6, PSMA5, PSMA1, MAPK6, PPP6C, PCMT1, YBX1, NPM1, NCL, MFAP4, LYZ, ILF3, ILF2, IARS, HSPD1, HSP90AB1, HSP90AA1, HSPA9, HSPA8, HSPA5, HSPA2, HSPA1A, HNRNPU, HNRNPA2B1,
    Protein Size: 403

    Poids moléculaire

    44 kDa

    ID gène

    6790

    NCBI Accession

    NM_198437, NP_940839

    UniProt

    O14965

    Pathways

    Cycle Cellulaire, Asymmetric Protein Localization
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