Aurora A anticorps (Middle Region)
Aperçu rapide pour Aurora A anticorps (Middle Region) (ABIN2785452)
Antigène
Voir toutes Aurora A (AURKA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- AURKA Antibody - middle region
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Séquence
- REKQSKFILA LKVLFKAQLE KAGVEHQLRR EVEIQSHLRH PNILRLYGYF
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 77%, Zebrafish: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against AURKA. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human AURKA
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53574-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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Autre désignation
- AURKA
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Sujet
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Background Information: AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. It is found at the centrosome in interphase cells and at the spindle poles in mitosis. This protein may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
Gene Name: aurora kinase C
Alternative Symbols: AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, PPP1R47
Protein Name: Aurora kinase A
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Poids moléculaire
- 44kDa
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ID gène
- 6790
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NCBI Accession
- NP_940839
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UniProt
- O14965
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Pathways
- Cycle Cellulaire, Asymmetric Protein Localization
Antigène
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