Aurora Kinase C anticorps (Middle Region)

N° du produit ABIN2785453

Cité dans 1 publication. Cet anticorps anti-Aurora Kinase C Polyclonal Lapin (ABIN2785453) détecte spécifiquement Aurora Kinase C dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour Aurora Kinase C anticorps (Middle Region) (ABIN2785453)

Antigène: Aurora Kinase C (AURKC)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aurora Kinase C est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Aurora Kinase C anticorps

Épitope: Middle Region

Fonction: AURKC Antibody - middle region

Séquence: TYDEKVDLWC IGVLCYELLV GYPPFESASH SETYRRILKV DVRFPLSMPL

Homologie: Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against AURKC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human AURKC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53575-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Aurora Kinase C (ABIN2785453)

Lee, Lim, Park, Lee, Han, Kim, Cheang, Lee, Lee, Ko, Jang, Kim, Miniaci, Bartsch, Kim, Bailey, Kandel, Kaang: "Nuclear translocation of CAM-associated protein activates transcription for long-term facilitation in Aplysia." dans: Cell, Vol. 129, Issue 4, pp. 801-12, (2007) (PubMed).

Détails sur Aurora Kinase C

Antigène: Aurora Kinase C (AURKC)

Autre désignation: AURKC

Sujet:

Background Information: AURKC may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis.This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

Gene Name: Aurora kinase C

Alternative Symbols: AIE2, AIK3, ARK3, AurC, SPGF5, STK13, HEL-S-90, aurora-C

Protein Name: Aurora kinase C

Poids moléculaire: 34kDa

ID gène: 6795

NCBI Accession: NP_001015878

UniProt: Q9UQB9

Pathways: Cycle Cellulaire, Maintenance of Protein Location