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SOCS7 anticorps (N-Term)
SOCS7
Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Porc, Cheval, Chien, Cobaye
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN2785525
Détail du produit anti-SOCS7 anticorps
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Antigène
Voir toutes SOCS7 Anticorps
SOCS7
(Suppressor of Cytokine Signaling 7 (SOCS7))
Épitope
Tous les épitopes à travers SOCS7 Anticorps.
N-Term
Reactivité
Humain, Souris, Rat, Boeuf (Vache), Lapin, Porc, Cheval, Chien, Cobaye
Hôte
Toutes les hôtes sur SOCS7 Anticorps
Lapin
Clonalité
Toutes les clonalités sur SOCS7 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers SOCS7 Anticorps
Cet anticorp SOCS7 est non-conjugé
Application
Tous les applications à travers SOCS7 Anticorps.
Western Blotting (WB)
Séquence
GSAGRELDAG RKPKLTRTQS AFSPVSFSPL FTGETVSLVD VDISQRGLTS
Homologie
Cow: 100%, Dog: 92%, Guinea Pig: 83%, Horse: 100%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 100%, Rat: 92%
Attributs du produit
This is a rabbit polyclonal antibody against SOCS7. It was validated on Western Blot.
Purification
Affinity Purified
Immunogène
The immunogen is a synthetic peptide directed towards the N-terminal region of Human SOCS7
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Discover our top product SOCS7 Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeat freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Détails sur SOCS7
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Antigène
SOCS7
(Suppressor of Cytokine Signaling 7 (SOCS7))
Autre désignation
SOCS7 (SOCS7 Produits )
Synonymes
anticorps NAP4, anticorps NCKAP4, anticorps SOCS4, anticorps SOCS6, anticorps 2310063P06Rik, anticorps C85125, anticorps Nap4, anticorps GB13951, anticorps zgc:175115, anticorps SOCS7, anticorps socs7, anticorps suppressor of cytokine signaling 7, anticorps suppressor of cytokine signaling, anticorps SOCS7, anticorps Socs7, anticorps LOC413772, anticorps socs7
Sujet
SOCS7 regulates signaling cascades probably through protein ubiquitination and/or sequestration. It functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. It inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. SOCS7 may be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Protein Interaction Partner: SEPT6, SORBS3, STAT5A, STAT3, CUL5, IRS4, PIK3R2, TUBB4B, TUBA1A, IRS2, NCK1, PLCG1, PIK3R1, EGFR, GRB2, Protein Size: 331
Poids moléculaire
36 kDa
ID gène
30837
Vus récemment
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