APH1B anticorps (N-Term)

N° du produit ABIN2785589

Cet anticorps Lapin Polyclonal détecte spécifiquement APH1B dans WB. Il présente une réactivité avec des échantillons de Souris, Humain, Rat, Lapin, Boeuf (Vache), Chien et Cobaye.

Aperçu rapide pour APH1B anticorps (N-Term) (ABIN2785589)

Antigène: APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))

Reactivité: Souris, Humain, Rat, Lapin, Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APH1B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-APH1B anticorps

Épitope: N-Term

Séquence: IIDNKDGPTQ KYLLIFGAFV SVYIQEMFRF AYYKLLKKAS EGLKSINPGE

Homologie: Cow: 92%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against APH1B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human APH1B

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur APH1B

Antigène: APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))

Autre désignation: APH1B

Sujet: This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein.
Alias Symbols: APH-1B, PRO1328, PSFL, TAAV688
Protein Interaction Partner: UBC, PSENEN, NCSTN, PSEN2, PSEN1,
Protein Size: 257

Poids moléculaire: 28 kDa

ID gène: 83464

NCBI Accession: NM_031301, NP_112591

UniProt: Q8WW43

Pathways: Signalisation Notch, Neurotrophin Signaling Pathway