ATG16L1 anticorps (N-Term)

N° du produit ABIN2785621

L’anticorps anti-ATG16L1 Polyclonal Lapin est utilisé pour la détection de ATG16L1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin et Cobaye. Il a été validé pour WB et IHC.

Aperçu rapide pour ATG16L1 anticorps (N-Term) (ABIN2785621)

Antigène: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG16L1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ATG16L1 anticorps

Épitope: N-Term

Fonction: ATG16L1 Antibody - N-terminal region

Séquence: QYNKLLEKSD LHSVLAQKLQ AEKHDVPNRH EISPGHDGTW NDNQLQEMAQ

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 91%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ATG16L1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ATG16L1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54268-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ATG16L1

Antigène: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Autre désignation: ATG16L1

Sujet:

Background Information: Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy.Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy (Mizushima et al., 2003 [PubMed 12665549]).[supplied by OMIM].

Gene Name: ATG16 autophagy related 16-like 1 (S. cerevisiae)

Alternative Symbols: IBD10, WDR30, APG16L, ATG16A, ATG16L

Protein Name: Autophagy-related protein 16-1

Poids moléculaire: 66kDa

ID gène: 55054

NCBI Accession: NP_060444

UniProt: Q676U5

Pathways: Autophagy