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ATG16L1 anticorps (Middle Region)

Cet anticorps anti-ATG16L1 est un anticorps Lapin Polyclonal détectant ATG16L1 dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cheval, Cobaye et Porc.
N° du produit ABIN2785624

Aperçu rapide pour ATG16L1 anticorps (Middle Region) (ABIN2785624)

Antigène

Voir toutes ATG16L1 Anticorps
ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Reactivité

  • 81
  • 36
  • 34
  • 10
  • 6
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cheval, Cobaye, Porc

Hôte

  • 68
  • 12
  • 1
Lapin

Clonalité

  • 60
  • 21
Polyclonal

Conjugué

  • 51
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Cet anticorp ATG16L1 est non-conjugé

Application

  • 55
  • 28
  • 26
  • 11
  • 11
  • 10
  • 8
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Séquence

    TSPVRAISRA ATKRLSQPAG GLLDSITNIF GRRSVSSFPV PQDNVDTHPG

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    Attributs du produit

    This is a rabbit polyclonal antibody against ATG16L1. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the middle region of human ATG16L1
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 607 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

    Autre désignation

    ATG16L1

    Sujet

    Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy.Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy (Mizushima et al., 2003 [PubMed 12665549]).[supplied by OMIM].
    Alias Symbols: APG16L, ATG16L, FLJ00045, FLJ10035, FLJ10828, FLJ22677, IBD10, WDR30, ATG16A
    Protein Interaction Partner: WIPI2, RB1CC1, DEDD2, TRAF3IP3, NOD2, TMEM59, TLR2, SUMO2, ATG13, ATG5, ULK1, UBC, TNK2, SYNPO2, ATG12, NOD1, WDFY3, APP, RAB33B, RAB35, RAB3D, RAB33A, HSPA4, FCGRT, CLTC, AP2M1, ELAVL1, MAP1LC3C, MAP1LC3B, ATG3, CCT2, CCT7, AGPS, GAN, CCT3, SNAPC4, ATG16
    Protein Size: 607

    Poids moléculaire

    68 kDa

    ID gène

    55054

    NCBI Accession

    NM_030803, NP_110430

    UniProt

    Q676U5

    Pathways

    Autophagy
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