ATG10 anticorps (C-Term)

N° du produit ABIN2785625

Cet anticorps Lapin Polyclonal détecte spécifiquement ATG10 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye et Cheval.

Aperçu rapide pour ATG10 anticorps (C-Term) (ABIN2785625)

Antigène: ATG10 (Autophagy Related 10 (ATG10))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG10 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ATG10 anticorps

Épitope: C-Term

Fonction: ATG10 Antibody - C-terminal region

Séquence: TPVLKNSQKI NKNVNYITSW LSIVGPVVGL NLPLSYAKAT SQDERNVP

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ATG10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ATG10

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8095316

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ATG10

Antigène: ATG10 (Autophagy Related 10 (ATG10))

Autre désignation: ATG10

Sujet:

Background Information: Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12-ATG5 conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A), a homolog of yeast Apg8, to a membrane-bound form.Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A, MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM].

Gene Name: ATG10 autophagy related 10 homolog (S. cerevisiae)

Alternative Symbols: APG10, APG10L, pp12616

Protein Name: Ubiquitin-like-conjugating enzyme ATG10

Poids moléculaire: 25kDa

ID gène: 83734

NCBI Accession: NP_113670

UniProt: Q9H0Y0

Pathways: ER-Nucleus Signaling, Autophagy