ERCC5 anticorps (N-Term)

N° du produit ABIN2785634

Détail du produit anti-ERCC5 anticorps

Antigène: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC5 est non-conjugé

Application: Western Blotting (WB)

Séquence: NPQAIDIESE DFSSLPPEVK HEILTDMKEF TKRRRTLFEA MPEESDDFSQ

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ERCC5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ERCC5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1186 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ERCC5

Antigène: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Autre désignation: ERCC5 (ERCC5 Produits)

Synonymes: anticorps COFS3, anticorps ERCM2, anticorps UVDR, anticorps XPG, anticorps XPGC, anticorps cofs3, anticorps ercm2, anticorps uvdr, anticorps xpg, anticorps xpgc, anticorps Xpg, anticorps ERCC excision repair 5, endonuclease, anticorps excision repair cross-complementation group 5 L homeolog, anticorps excision repair cross-complementing rodent repair deficiency, complementation group 5, anticorps ERCC5, anticorps ercc5.L, anticorps Ercc5

Sujet: Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, but the biological validity of all variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: COFS3, ERCM2, UVDR, XPG, XPGC
Protein Interaction Partner: UBC, CDK7, GTF2H1, POLR2A, EWSR1, ERCC6, SUMO2, PIDD1, BCL6, TAF10, ERCC3, NTHL1, GTF2H4, PCNA, ERCC2,
Protein Size: 1186

Poids moléculaire: 133 kDa

ID gène: 2073

NCBI Accession: NM_000123, NP_000114

UniProt: P28715

Pathways: Réparation de l'ADN