Hexokinase 2 anticorps (Middle Region)

N° du produit ABIN2785643

L’anticorps Lapin Polyclonal anti-Hexokinase 2 a été validé pour WB. Il convient pour détecter Hexokinase 2 dans des échantillons de Humain, Souris, Rat, Chien, Lapin, Porc, Boeuf (Vache), Cheval et Cobaye.

Aperçu rapide pour Hexokinase 2 anticorps (Middle Region) (ABIN2785643)

Antigène: Hexokinase 2 (HK2)

Reactivité: Humain, Souris, Rat, Chien, Lapin, Porc, Boeuf (Vache), Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hexokinase 2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Hexokinase 2 anticorps

Épitope: Middle Region

Séquence: QRIKENKGEE RLRSTIGVDG SVYKKHPHFA KRLHKTVRRL VPGCDVRFLR

Homologie: Cow: 79%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HK2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human HK2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 917 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Hexokinase 2

Antigène: Hexokinase 2 (HK2)

Autre désignation: HK2

Sujet: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. HK2 (hexokinase 2) is the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this protein is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Alias Symbols: DKFZp686M1669, HKII, HXK2
Protein Interaction Partner: UBQLN1, MAGEA12, SUMO2, SUMO3, UBC, EGFR, rev, H2AFV, WDR61, ARIH2, PDLIM1, PYGL, NUBP1, IPO5, HEXB, FNTA, FBXO6, PARK2, UBD, ITGA4, NUDCD3, UBQLN4, SLC2A4, ELAVL1, PTGDS, ZBTB17, PRKCE, IGFBP4,
Protein Size: 917

Poids moléculaire: 102 kDa

ID gène: 3099

NCBI Accession: NM_000189, NP_000180

UniProt: P52789

Pathways: Signalisation PI3K-Akt, Carbohydrate Homeostasis, L'effet Warburg