ACADVL anticorps (N-Term)
Aperçu rapide pour ACADVL anticorps (N-Term) (ABIN2785735)
Antigène
Voir toutes ACADVL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- RPYAGGAAQE SKSFAVGMFK GQLTTDQVFP YPSVLNEEQT QFLKELVEPV
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against ACADVL. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACADVL
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 633 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Identification of tyrosine-nitrated proteins in HT22 hippocampal cells during glutamate-induced oxidative stress." dans: Cell proliferation, Vol. 43, Issue 6, pp. 584-93, (2010) (PubMed).
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: "Identification of tyrosine-nitrated proteins in HT22 hippocampal cells during glutamate-induced oxidative stress." dans: Cell proliferation, Vol. 43, Issue 6, pp. 584-93, (2010) (PubMed).
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- ACADVL (Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))
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Autre désignation
- ACADVL
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Sujet
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ACADVL is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in ACADVL protein reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy.The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: ACAD6, LCACD, VLCAD
Protein Interaction Partner: EEF2K, GPHN, RPSA, ATF2, CDH1, INTS9, ATP5L, UBC, SOCS3, ICT1, ACADVL,
Protein Size: 633 -
Poids moléculaire
- 64 kDa
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ID gène
- 37
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NCBI Accession
- NM_001033859, NP_001029031
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UniProt
- P49748
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Pathways
- ER-Nucleus Signaling, Monocarboxylic Acid Catabolic Process
Antigène
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