14-3-3 sigma/SFN anticorps (Middle Region)

N° du produit ABIN2785886

Cet anticorps Lapin Polyclonal détecte spécifiquement 14-3-3 sigma/SFN dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Mouton, Cheval, Lapin, Cobaye, Saccharomyces cerevisiae et Poisson zèbre (Danio rerio).Il a été cité dans 1 publication.

Aperçu rapide pour 14-3-3 sigma/SFN anticorps (Middle Region) (ABIN2785886)

Antigène: 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Mouton, Cheval, Lapin, Cobaye, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 14-3-3 sigma/SFN est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-14-3-3 sigma/SFN anticorps

Épitope: Middle Region

Fonction: SFN Antibody - middle region

Séquence: FHYEIANSPE EAISLAKTTF DEAMADLHTL SEDSYKDSTL IMQLLRDNLT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 93%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SFN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SFN

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54792-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-14-3-3 sigma/SFN (ABIN2785886)

Lu, Zhu, Wen, Yang, Shaw, Lammer, Finnell: "Nicotinamide N-methyl transferase (NNMT) gene polymorphisms and risk for spina bifida." dans: Birth defects research. Part A, Clinical and molecular teratology, Vol. 82, Issue 10, pp. 670-5, (2008) (PubMed).

Détails sur 14-3-3 sigma/SFN

Antigène: 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

Autre désignation: SFN

Sujet:

Background Information: SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.

Gene Name: Stratifin

Alternative Symbols: YWHAS

Protein Name: 14-3-3 protein sigma

Poids moléculaire: 28kDa

ID gène: 2810

NCBI Accession: NP_006133

UniProt: P31947

Pathways: Signalisation p53, Myometrial Relaxation and Contraction