TBK1 anticorps (Middle Region)

N° du produit ABIN2785953

Détail du produit anti-TBK1 anticorps

Antigène: TBK1 (TANK-Binding Kinase 1 (TBK1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cheval, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBK1 est non-conjugé

Application: Western Blotting (WB)

Séquence: QEGTHPKDRN VEKLQVLLNC MTEIYYQFKK DKAERRLAYN EEQIHKFDKQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against TBK1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TBK1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 729 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TBK1

Antigène: TBK1 (TANK-Binding Kinase 1 (TBK1))

Autre désignation: TBK1 (TBK1 Produits)

Synonymes: anticorps nak, anticorps t2k, anticorps TBK1, anticorps wu:fk70c05, anticorps zgc:136548, anticorps NAK, anticorps T2K, anticorps 1200008B05Rik, anticorps AI462036, anticorps AW048562, anticorps TANK binding kinase 1 L homeolog, anticorps TANK binding kinase 1, anticorps TANK-binding kinase 1, anticorps tbk1.L, anticorps TBK1, anticorps tbk1, anticorps Tbk1

Sujet: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitinat
Alias Symbols: FLJ11330, NAK, T2K
Protein Interaction Partner: UBC, Trim11, AZI2, TBK1, TANK, TBKBP1, EGFR, TMEM173, TRAF3, EXOC2, MIB1, LATS2, ANKRD28, DDX58, SYK, TRAF3IP2, TOMM70A, STX11, PROS1, IRF3, HSP90AA1, XIAP, RNF11, YWHAE, APP, NFKBIA, IKBKG, TRAF2, MAVS, OPTN, SRC, RELA, TICAM1, MBP, IRF7, IKBKE, HERC2, T
Protein Size: 729

Poids moléculaire: 84 kDa

ID gène: 29110

NCBI Accession: NM_013254, NP_037386

UniProt: Q9UHD2

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome