PIK3R5 anticorps (N-Term)

N° du produit ABIN2786003

Cet anticorps Lapin Polyclonal détecte spécifiquement PIK3R5 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache) et Poisson zèbre (Danio rerio).

Aperçu rapide pour PIK3R5 anticorps (N-Term) (ABIN2786003)

Antigène: PIK3R5 (Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3R5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PIK3R5 anticorps

Épitope: N-Term

Fonction: PIK3R5 Antibody - N-terminal region

Séquence: HRFLTWPVPY CSICQELLTF IDAELKAPGI SYQRLVRAEQ GLPIRSHRSS

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against PIK3R5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PIK3R5

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55011-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PIK3R5

Antigène: PIK3R5 (Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))

Autre désignation: PIK3R5

Sujet:

Targeted Subunit: 5

Background Information: Receptor-regulated class I phosphoinositide 3-kinases (PI3Ks) phosphorylate the membrane lipid phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to PtdIns(3,4,5)P3, which in turn recruits and activates cytosolic effectors involved in proliferation, survival, or chemotaxis. PIK3R5 is a PI3K regulatory subunit.Receptor-regulated class I phosphoinositide 3-kinases (PI3Ks) phosphorylate the membrane lipid phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to PtdIns(3,4,5)P3, which in turn recruits and activates cytosolic effectors involved in proliferation, survival, or chemotaxis. PIK3R5 is a PI3K regulatory subunit (Brock et al., 2003 [PubMed 12507995]).[supplied by OMIM]. Sequence Note: removed 2 bases from the 3' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-3253 AF128881.1 1-3253

Gene Name: Phosphoinositide-3-kinase, regulatory subunit 5

Alternative Symbols: p101, FOAP-2, P101-PI3K, F730038I15Rik

Protein Name: Phosphoinositide 3-kinase regulatory subunit 5

Poids moléculaire: 97kDa

ID gène: 23533

NCBI Accession: NP_055123

UniProt: Q8WYR1

Pathways: Signalisation PI3K-Akt, Inositol Metabolic Process, Hepatitis C, VEGF Signaling