SENP1 anticorps (Middle Region)
Aperçu rapide pour SENP1 anticorps (Middle Region) (ABIN2786045)
Antigène
Voir toutes SENP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- PQQMNGSDCG MFACKYADCI TKDRPINFTQ QHMPYFRKRM VWEILHRKLL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%
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Attributs du produit
- This is a rabbit polyclonal antibody against SENP1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human SENP1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 643 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))
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Autre désignation
- SENP1
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Sujet
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The covalent modification of proteins by the small ubiquitin-like protein SUMO is implicated in the regulation of nucleocytoplasmic transport, genomic stability, gene transcription, and other processes. Sumoylation is catalyzed on target lysine residues by a multienzyme process and is reversed by desumoylating enzymes such as SENP1.
Alias Symbols: SuPr-2
Protein Interaction Partner: USP25, RABGAP1, SUMO1, TP53, SP100, SUMO2, SUMO3, RANGAP1, PRDM1, BAG3, LMNA, APP, UBD, U90, HIPK2, ISG15, RANBP2, HDAC2, ELAVL1, UBC, GCM1, RUVBL2, HDAC1, PARP1, HDAC4, KCNK1, SENP1, SP3,
Protein Size: 643 -
Poids moléculaire
- 73 kDa
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ID gène
- 29843
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NCBI Accession
- NM_014554, NP_055369
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Pathways
- Positive Regulation of Endopeptidase Activity
Antigène
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