DAAM1 anticorps (Middle Region)

N° du produit ABIN2786070

L’anticorps anti-DAAM1 Polyclonal Lapin est utilisé pour la détection de DAAM1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio) et Chien. Il a été validé pour WB.

Aperçu rapide pour DAAM1 anticorps (Middle Region) (ABIN2786070)

Antigène: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAAM1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DAAM1 anticorps

Épitope: Middle Region

Fonction: DAAM1 Antibody - middle region

Séquence: GNTVQYWLLL DRIIQQIVIQ NDKGQDPDST PLENFNIKNV VRMLVNENEV

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against DAAM1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human DAAM1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55131-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur DAAM1

Antigène: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Autre désignation: DAAM1

Sujet:

Background Information: Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein.Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.

Gene Name: Dishevelled associated activator of morphogenesis 1

Alternative Symbols: FLJ41657, KIAA0666

Protein Name: Disheveled-associated activator of morphogenesis 1

Poids moléculaire: 123kDa

ID gène: 23002

NCBI Accession: NP_055807

UniProt: Q9Y4D1

Pathways: Signalisation WNT