Spartin (SPART) (Middle Region) anticorps

N° du produit ABIN2786078

Cet anticorps anti-Spartin Polyclonal Lapin (ABIN2786078) détecte spécifiquement Spartin dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Poisson zèbre (Danio rerio), Lapin, Cheval, Cobaye, Chien et Boeuf (Vache).

Aperçu rapide pour Spartin (SPART) (Middle Region) anticorps (ABIN2786078)

Antigène: Spartin (SPART)

Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Lapin, Cheval, Cobaye, Chien, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Détail du produit

Épitope: Middle Region

Fonction: SPART Antibody - middle region

Séquence: ASWVSWGLVK GAEITGKAIQ KGASKLRERI QPEEKPVEVS PAVTKGLYIA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SPG20. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SPG20

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55162-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détail du antigène

Antigène: Spartin (SPART)

Autre désignation: SPART

Sujet:

Background Information: This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).

Gene Name: spartin

Alternative Symbols: SPG20, TAHCCP1

Protein Name: spartin

Poids moléculaire: 73kDa

ID gène: 23111

NCBI Accession: NP_055902

UniProt: Q8N0X7