PDE4D anticorps (C-Term)
Aperçu rapide pour PDE4D anticorps (C-Term) (ABIN2786831)
Antigène
Voir toutes PDE4D AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- FQFELTLEED GESDTEKDSG SQVEEDTSCS DSKTLCTQDS ESTEIPLDEQ
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against PDE4D. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human PDE4D
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))
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Autre désignation
- PDE4D
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Sujet
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This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
Protein Interaction Partner: MAGEA6, GOLGA8F, GOLGA8EP, COIL, TRAF1, ZBTB1, HDGFRP2, BIN1, MAPK1, PIAS4, PRKACA, UBC, SRC, SPTBN1, PIK3CA, LYN, GRB2, FYN, ARRB2, ARRB1, ABL1, APP, PAFAH1B1, CDK2, PPP3R1, PPP3CB, PPP3CA, GSK3B, CSNK1A1, ITSN1, SUMO2, GNB2L1, MDM2, Bub1, PDE4DIP, AKAP6
Protein Size: 507 -
Poids moléculaire
- 55 kDa
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ID gène
- 5144
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Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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