ELP2 anticorps (Middle Region)

N° du produit ABIN2787102

Cet anticorps Lapin Polyclonal détecte spécifiquement ELP2 dans WB. Il présente une réactivité envers Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour ELP2 anticorps (Middle Region) (ABIN2787102)

Antigène: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ELP2 anticorps

Épitope: Middle Region

Séquence: EESGVWLEQV RVGEVGGNTL GFYDCQFNED GSMIIAHAFH GALHLWKQNT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against ELP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ELP2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 826 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ELP2

Antigène: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Autre désignation: ELP2

Sujet: ELP2 regulates the ligand-dependent activation of STAT3. ELP2 acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.
Alias Symbols: FLJ10879, SHINC-2, STATIP1, StIP
Protein Interaction Partner: UBC, FAM96B, CIAO1, PAAF1, WRNIP1, ELP3, NRBP1, CD2AP, KIAA1033, USP34, SNRPB2, PRPSAP2, KIF5B, MMS19, IKBKAP, ELP4, CTDP1, STAT5B, STAT1, JAK2, JAK1, STAT3, TYK2,
Protein Size: 826

Poids moléculaire: 92 kDa

ID gène: 55250

NCBI Accession: NM_018255, NP_060725

UniProt: Q6IA86

Pathways: Stem Cell Maintenance, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus