RORC anticorps (N-Term)
Aperçu rapide pour RORC anticorps (N-Term) (ABIN2499787)
Antigène
Voir toutes RORC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- MDRAPQRQHR ASRELLAAKK THTSQIEVIP CKICGDKSSG IHYGVITCEG
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Homologie
- Cow: 100%, Dog: 96%, Guinea Pig: 79%, Horse: 88%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against RORC. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human RORC
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RORC (RAR-Related Orphan Receptor C (RORC))
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Autre désignation
- RORC
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Sujet
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RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.
Alias Symbols: NR1F3, RORG, RZR-GAMMA, RZRG, TOR
Protein Interaction Partner: EVI2A, NCOA6, EIF3I, CHD4, EIF4EBP1,
Protein Size: 518 -
Poids moléculaire
- 58 kDa
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ID gène
- 6097
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NCBI Accession
- NM_005060, NP_005051
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UniProt
- Q6I9R9
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Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
Antigène
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