H2AFY anticorps (Middle Region)

N° du produit ABIN2787622

Détail du produit anti-H2AFY anticorps

Antigène: H2AFY (H2A Histone Family, Member Y (H2AFY))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp H2AFY est non-conjugé

Application: Western Blotting (WB)

Séquence: PVSKKAGGKK GARKSKKQGE VSKAASADST TEGTPADGFT VLSTKSLFLG

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against H2AFY. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human H2AFY

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 371 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur H2AFY

Antigène: H2AFY (H2A Histone Family, Member Y (H2AFY))

Autre désignation: H2AFY (H2AFY Produits)

Synonymes: anticorps H2A.y, anticorps H2A/y, anticorps H2AF12M, anticorps H2AFJ, anticorps MACROH2A1.1, anticorps mH2A1, anticorps macroH2A1.2, anticorps mH2a1, anticorps macroH2A1, anticorps wu:fa93c12, anticorps zgc:136891, anticorps h2a.y, anticorps h2a/y, anticorps h2af12m, anticorps h2afj, anticorps macroh2a, anticorps mh2a1, anticorps core histone macro-H2A.1, anticorps H2A histone family, member Y, anticorps H2A histone family member Y, anticorps H2A histone family member Y L homeolog, anticorps LOC100230612, anticorps H2AFY, anticorps LOC481514, anticorps H2afy, anticorps h2afy, anticorps h2afy.L

Sujet: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H2AFY is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: H2A.y, H2A/y, H2AF12M, H2AFJ, MACROH2A1.1, mH2A1, macroH2A1.2
Protein Interaction Partner: ERICH2, UBC, SUMO2, SUMO3, HIST1H3A, H3F3A, SUZ12, EED, RNF2, EZH2, BMI1, SRPK1, LMNA, ATF2, FN1, HIST1H3B, CENPA, APP, CBX5, CBX3, DIDO1, UBD, ATXN1L, NEDD8, ERBB2, SUMO1, HDGF, HDAC2, HDAC1, PARP1, tat, CUL3, SPOP, WDR77, PHF14, DEK, XRCC5, TOP1, RAN, H
Protein Size: 371

Poids moléculaire: 39 kDa

ID gène: 9555

NCBI Accession: NM_001040158, NP_001035248

UniProt: O75367