TINF2 anticorps (Middle Region)

N° du produit ABIN2787641

Détail du produit anti-TINF2 anticorps

Antigène: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Épitope: Middle Region

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Porc, Rat, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TINF2 est non-conjugé

Application: Western Blotting (WB)

Séquence: SDEEENGQGE GKESLENYQK TKFDTLIPTL CEYLPPSGHG AIPVSSCDCR

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against TINF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TINF2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 451 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TINF2

Antigène: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Autre désignation: TINF2 (TIN2 Produits)

Synonymes: anticorps DKCA3, anticorps TIN2, anticorps AW552114, anticorps D14Wsu146e, anticorps Tin2, anticorps TERF1 interacting nuclear factor 2, anticorps Terf1 (TRF1)-interacting nuclear factor 2, anticorps TINF2, anticorps Tinf2

Sujet: TINF2 is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. It plays a role in shelterin complex assembly.
Alias Symbols: TIN2, DKCA3
Protein Interaction Partner: ACD, TERF2, TPP1, ANXA8L1, TNKS, TERF1, VIPR1, ZNF790, PAGE2, TUBB, DHFRL1, APOBEC3F, REM2, NUDCD2, CCDC43, SCRN2, TRIM15, TXNDC17, AFAP1L2, FERMT3, KCTD17, ANKMY2, PPP6R3, PGM2, APPL2, BIN2, LGALSL, PHPT1, GNMT, OR2H1, CCDC9, POT1, AIPL1, NCDN, ACOT7, TO
Protein Size: 451

Poids moléculaire: 50 kDa

ID gène: 26277

NCBI Accession: NM_001099274, NP_001092744

UniProt: Q9BSI4

Pathways: Cycle Cellulaire, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process