CDK1 anticorps (Middle Region)

N° du produit ABIN2787664

L’anticorps Lapin Polyclonal anti-CDK1 a été validé pour WB. Il convient pour détecter CDK1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Mouton, Lapin, Poisson zèbre (Danio rerio), Cobaye, Chévre et Cheval.

Aperçu rapide pour CDK1 anticorps (Middle Region) (ABIN2787664)

Antigène: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Mouton, Lapin, Poisson zèbre (Danio rerio), Cobaye, Chévre, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDK1 anticorps

Épitope: Middle Region

Séquence: DYKNTFPKWK PGSLASHVKN LDENGLDLLS KMLIYDPAKR ISGKMALNHP

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 83%

Attributs du produit: This is a rabbit polyclonal antibody against CDC2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CDC2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 240 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CDK1

Antigène: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Autre désignation: CDC2

Sujet: The protein encoded by CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Alias Symbols: CDC28A, CDK1, DKFZp686L20222, MGC111195, CDC2, P34CDC2
Protein Interaction Partner: ABL1, SIRT1, CDC37, HUWE1, BTRC, UBC, HSP90AA1, HSPA4, HIST1H1A, GADD45A, CKS1B, USP16, Samhd1, UIMC1, SUMO2, CCNA2, STAU1, RNF2, CKS2, ZRANB2, CDKN1B, CDKN1A, CDK1, CCNB1, FBXO6, CCNB2, PKMYT1, SQSTM1, EGFR, PTMA, DCTN6, RGCC, BAG3, CDC25B, BCL2, TP53BP1
Protein Size: 240

Poids moléculaire: 27 kDa

ID gène: 983

NCBI Accession: NM_033379, NP_203698

UniProt: P06493

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA