AXL anticorps (C-Term)

N° du produit ABIN2787910

Cet anticorps Lapin Polyclonal détecte spécifiquement AXL dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Cobaye et Cheval.

Aperçu rapide pour AXL anticorps (C-Term) (ABIN2787910)

Antigène: AXL (AXL Receptor tyrosine Kinase (AXL))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AXL est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-AXL anticorps

Épitope: C-Term

Séquence: QPDPKDSCSC LTAAEVHPAG RYVLCPSTTP SPAQPADRGS PAAPGQEDGA

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 86%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against AXL. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human AXL

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 885 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AXL

Antigène: AXL (AXL Receptor tyrosine Kinase (AXL))

Autre désignation: AXL

Sujet: The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: JTK11, UFO
Protein Interaction Partner: RANBP9, UBC, TYRO3, FBXO25, STUB1, HSP90AA1, HSPA1A, ERRFI1, TNK2, ELAVL1, CBL, SHC3, SOCS1, PIK3R2, ADAM10, SHC1, GAS6, SRC, PTPN11, PLCG1, PIK3R1, LCK, AXL, GRB2, TENC1, PIK3R3, NCK2,
Protein Size: 885

Poids moléculaire: 97 kDa

ID gène: 558

NCBI Accession: NM_001699, NP_001690

UniProt: P30530

Pathways: Signalisation RTK, Cellular Response to Molecule of Bacterial Origin