CD4 anticorps (C-Term)

N° du produit ABIN2787938

Cet anticorps Lapin Polyclonal détecte spécifiquement CD4 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Mouton, Cobaye, Chévre et Cheval.

Aperçu rapide pour CD4 anticorps (C-Term) (ABIN2787938)

Antigène: CD4

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Mouton, Cobaye, Chévre, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD4 anticorps

Épitope: C-Term

Séquence: VLGGVAGLLL FIGLGIFFCV RCRHRRRQAE RMSQIKRLLS EKKTCQCPHR

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CD4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CD4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 458 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD4

Antigène: CD4

Autre désignation: CD4

Sujet: This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Alias Symbols: CD4mut
Protein Interaction Partner: env, RANBP9, vpu, ADRB2, UBC, CXCR4, UBL7, ABCB1, INPPL1, VCP, HGS, LCK, NR3C1, STUB1, TUBB, MYL12A, DHRS2, LRPPRC, FARSB, EIF3I, EIF3D, EIF3C, EIF3B, VIM, VDAC3, VDAC2, VDAC1, SSRP1, RPS19, RPS12, RPS10, RPS9, RPLP1, RPLP0, RPL22, RPL18, RPL7, PHB, NPM1,
Protein Size: 458

Poids moléculaire: 48 kDa

ID gène: 920

NCBI Accession: NM_000616, NP_000607

UniProt: P01730

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events